Molecular Diagnostics at IMD
Hemtaolymphoid Interactive Chart
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Test/Probes:
Leukemia & Lymphoma Panel
Pro-B Cell Add-on
Clinical Utility:
Diagnostic
Projected Turnaround Time:
PB 8-24 Hours
BM 8-24 Hours
Test/Probes:
Chromosome Analysis
Clinical Utility:
Diagnostic
Prognostic
Predictive Therapeutic
Specimen Requirements:
- Minimum 2 mL
Projected Turnaround Time:
5-10 days
- t(1:19) TCF/PBX1
- del(6q) CCND/SEC63/MYB
- del(9q) CDKN2A
- 11q23 KMT2A rearrangements
- 12q32 IGH rearrangements
T-CELL OPTIONAL MARKERS:
- 14q11.2 TRA rearrangements
- 7q34 TRB rearrangements
- 10q24 TLX1
- 5q35 TLX3
- IMDseq Myeloid Profile
- B-Cell Clonality
- T-Cell Clonality
- BCF/ABL1 1 qPCR
- BCR/ABL1 Kinase Domain Mutation
Leukemia & Lymphoma Panel
- Blast Lineage add-on
- Monocyte add-on
Chromosome Analysis
- inv(3) MECOM rearrangements
- t(8;21) RUNX1T1/RUNX1
- t(9;22) BCR/ABL 1/ASS1
- 11q23 KMT2A rearrangements
- t(15/17) PML/RARA
- inv(16), t(16;16) CBFB rearrangements
- 17q RARA rearrangements
- IMDseq Myeloid Profile
- FLT3 mutation
- NPM1 mutation
- CEBPA mutation
- IDH1/IDH2 mutation
- KIT mutation in AML
- TP53 mutation
- PML/RARA mutation
- CBFB/MYH11 qPCR
- RUNX1/RUNX1T1 (AML/ETO) qPCR
Leukemia & Lymphoma Panel
- B-Lymphoma add-on
- T-Lymphoma add-on
Chromosome Analysis
- del(6q) CCND3/SEC63/MYB
- del(11q) ATM
- t(11;14) CCND1/IGH
- Trisomy 12
- del(13q) 13q14/13q34
- del(17q) TP53
- IMDseq Myeloid Profile
- B-Cell Clonality Assay
- GHV Somatic Hypermutation
- TP53 Mutation