Fish Probe Panel

Chronic Lymphocytic Leukemia (CLL) Panel
  • del(6q) CCND3/SEC63/MYB
  • del(11q) ATM
  • t(11;14) CCND1/IGH
  • Trisomy 12
  • del(13q) 13q14/13q34
  • del(17q) TP53
Myelodysplastic Syndrome (MDS) Panel
  • del(5q) EGR1
  • del(7q)/monosomy 7
  • Trisomy 8
  • del(20q)
  • 11q23 KMT2A rearrangements
Myeloproliferative Neoplasm (MPN) Panel
  • del(5q) EGR1
  • del(7q)/monosomy 7
  • trisomy 8
  • del(20q)
  • t(9;22) BCR/ABL1/ASS1
  • 4q12 FIP1L1/CHIC2/PDGFRA
  • 5q33 PDGFRB rearrangements
  • 8p11 FGFR1 rearrangements
Pediatric Acute Lymphocytic Leukemia (ALL) Panel
  • t(1;19) TCF3/PBX1
  • trisomy 4,10,17
  • t(9;22) BCR/ABL1/ASS1
  • 11q23 KMT2A rearrangements
  • t(12;21) ETV6/RUNX1
  • 14q32 IGH rearrangement
Acute Myelogenous Leukemia (AML) Panel
  • t(15;17) PML/RARA
  • t(9;22) BCR/ABL1/ASS1
  • t(8;21) RUNX1T1/RUNX1
  • 11q23 KMT2A rearrangements
  • inv(16), t(16;16) CBFB rearrangements
  • inv(3) MECOM rearrangements
  • 17q RARA rearrangements
Adult B-Cell Acute Lymphocytic Leukemia (ALL) Panel
  • t(1;19) TCF3/PBX1
  • del(6q) CCND3/SEC63/MYB
  • del(9p) CDKN2A
  • t(9;22) BCR/ABL1/ASS1
  • 14q32 IGH rearrangements
  • 11q23 KMT2A rearrangements
Chronic Myelogenous Leukemia (CML) Panel
  • t(9;22) BCR/ABL1/ASS1
  • trisomy 8
  • i(17q)
  • 14q11.2 TRA rearrangement
T-Cell Leukemia/Lymphoma Panel
  • 2p23 ALK rearrangements
  • 5q35 TLX3
  • 7q34 TRB rearrangements
  • i(7q) 7cen/7q22/7q31
  • 10q24 TLX1
  • 14q11.2 TRA rearrangements
  • 14q32 TCL1A
Adult T-Cell Acute Lymphocytic Leukemia (ALL) Panel
  • 5q35 TLX3
  • 7q34 TRB rearrangement
  • del(9p) CDKN2A
  • 10q24 TLX1
  • UroVysion
  • ALK Lung Cancer
  • ROS1 Lung Cancer
Lymphoma Probes
  • 3q27 BCL6 rearrangements (Diffused Large B-Cell, Follicular, Marginal Zone B-Cell)
  • t(8;14) MYC/IGH (Burkitt or Follicular)
  • 8q24 MYC rearrangements
  • t(11;14) CCND1/IGH (Mantle Cell)
  • t(11;18) BIRC3/MALT1
  • t(14;18) IGH/BCL2 (Follicular or Diffused Large B-Cell)
  • 18q21 BCL2 rearrangements
  • 18q21 MALT1 rearrangements
Multiple Myeloma (MM) Panel
  • 1p32.3/1q21 CDKN2C/CKS1B
  • t(4;14) FGFR3/IGH
  • trisomy 5
  • t(6;14) CCND3/IGH
  • 8q24 MYC rearrangements
  • t(11;14) CCND1/IGH
  • del(13q) 13q14/13q34
  • t(14;16) IGH/MAF
  • t(14;20) IGH/MAFB
  • del(17p) TP53
Solid Tumor Probes
  • EWSR1 Ewing Sarcoma
  • FOXO1 Alveolar Rhabdomyosarcoma
  • DDIT3 (CHOP) Myxoid Liposarcoma
  • LOH 1p/19q Glioma
  • MYCN 2p24.1 Neuroblastoma
  • SS18 Synovial Sarcoma
  • MDM2 12q15 Well-Differentiated Liposarcoma
  • UroVysion
  • ALK Lung Cancer
  • ROS1 Lung Cancer
Transplant
  • XX/XY for sex mismatched transplants